Introduction

The course aims to contribute to solid training based on current knowledge derived from basic and clinical research in oncology.
The topics addressed will include patient-derived organoids, tumor immunology, cancer biomarkers, cancer treatment, and drug resistance!
All students, former students, supervisors, and teachers are welcome.



Organizing Committee

  • Carmen Jerónimo (IPO Porto/ICBAS-UP)
  • Irina Amorim (ICBAS-UP/IPATIMUP-i3S)
  • Diana Machado
  • Fernanda Pontes
  • Mariana Costa
  • Ruben Sousa
  • Rui Pereira

Scientific Committee

  • Carmen Jerónimo (IPO Porto/ICBAS-UP)
  • Cláudia Vieira (IPO Porto /ICBAS-UP)
  • Irina Amorim (ICBAS-UP/IPATIMUP-i3S)
  • Isabel Bravo (IPO Porto)
  • Carina Pereira (IPO Porto)
  • Manuel R. Teixeira (IPO Porto/ICBAS-UP)
  • Margareta P. Correia (IPO Porto)
  • Maria José Oliveira (i3S/ICBAS-UP)
  • Nuno Vale (FMUP)
  • Paula Paulo (IPO Porto)
  • Rui Henrique (IPO Porto/ICBAS-UP)
  • Rui Medeiros (IPO Porto//UFP/ICBAS-UP)
  • Sara Monteiro-Reis (IPO Porto/INEGI)

Program


  • 08h30 | Opening session

    • Prof. Carmen Jerónimo
    • Prof. Irina Amorim
    • Prof. Henrique Cyrne de Carvalho (Director of ICBAS)
    • Dr. Júlio Oliveira (Director of IPO Porto)

  • 09h00 | FORMER STUDENTS’ CORNER

    Chairs: Carmen Jerónimo (IPO Porto/ICBAS-UP) & Irina Amorim (ICBAS-UP/i3S)
    • 09h00 | “Deciphering the molecular and genomic landscapes in the progression of serrated intestinal tumours”
      Miguel Silva PhD (Ludwig-Maximilians-Universität (LMU), Munich - MSc in Oncology, 2013)
    • 09h30 | KEYNOTE LECTURE: “Patient-derived organoids to investigate drug response and treatment resistance mechanisms in urological cancers”
      Clémentine Le Magnen, PhD (Laboratory for Translational GU Cancer Research | University Hospital Basel)


  • 10h15 | STUDENTS’ PRESENTATIONS
    Biomarkers (Detection, Prognosis & Prediction) I

    Chairs: Carina Pereira (IPO Porto) & Sara Monteiro-Reis (IPO Porto/INEGI)
    • 10h15 | “Extracelullar Vesicles-Derived microRNAs as Potencial Therapeutic Targets in Renal Cell Carcinoma”
      Ângela Maria Amorim Alves
    • 10h30 | “Epimarkers for Lung Cancer screening in liquid biopsies (EpiLungScreen)”
      Diana Inês Alves Pinto Carvalho Machado
    • 10h45 | “The interplay between epigenetics and metabolism in sarcomatoid Renal Cell Carcinoma: A novel era for biomarkers?”
      Fernanda Isabel Fernandes Pontes

  • 11h00 | Coffee-Break


  • 11h15 | STUDENTS’ PRESENTATIONS
    Tumor Immunology

    Chairs: Maria José Oliveira (i3S/ICBAS-UP) & Margareta Correia (IPO Porto)
    • 11h15 | “Unveil the mechanisms of CCL18-mediated colorectal cancer cell invasion”
      Ana Catarina Ferreira Ribeiro
    • 11h30 | “Exploring the Impact of Glycosylation on Macrophage Polarization in the Context of Tumour Progression (GlycoMAPP)”
      Camila Adriana Gonçalves Lourenço
    • 11h45 | “Prostate Cancer Immune Landscape Throughout Disease Progression”
      Mariana Lima da Costa

  • 12h00 | STUDENTS’ PRESENTATIONS
    Drugs & Therapy

    Chairs: Nuno Vale (FMUP) & Paula Paulo (IPO Porto)
    • 12h00 | “Interference of tamoxifen with therapeutic drugs used in obese and diabetic patients”
      Beatriz da Rocha Cunha
    • 12h15 | “Drug Repurposing for Application in Neuro-Oncology Using the Dopamine synthesis Cascade Pathway”
      Catarina Filipa de Sousa Moura
    • 12h30 | “Deciphering horizontal transmission of resistance in lung cancer: The role of caveolae-dependent endocytosis”
      Luana Beatriz Reis Pais Pereira

  • 12h45 | Lunch-Break


  • 14h30 | STUDENTS’ PRESENTATIONS
    Biomarkers (Detection, Prognosis & Prediction) II

    Chairs: Manuel R. Teixeira (IPO Porto/ICBAS-UP) & Rui Henrique (IPO Porto/ICBAS-UP)
    • 14h30 | “miRNA downregulation dynamics during acquisition of enzalutamide resistance: Implications for early detection and RNA-based therapeutic approaches”
      Mariana Filipa Couto Ferreira
    • 14h45 | “Epigenetic Insights Into Chronotype-Integrated Radiotherapy For Prostate Cancer - Predicting The Impact On Efficacy And Toxicity Of Treatment Timing With Circadian Rhythms (CIRCA-PREDICT)”
      Rúben Diogo Oliveira Sousa
    • 15h00 | “Urine-Derived Biomarkers for Immunotherapy Prediction Response in Urothelial Cancer – UrIPredict”
      Rui Pedro Ribeiro Pereira

  • 15h45 | STUDENTS’ PRESENTATIONS
    Clinical Research

    Chairs: Cláudia Vieira (IPO Porto) & Isabel Bravo (IPO Porto)
    • 15h45 | “Contribution of FDG:PET/CT in the Therapeutic Guidance of Lung Cancer Patients Treated with Chemotherapy and Radiotherapy”
      Maria de Fátima Garcia de Sousa Lopes
    • 16h15 | “ReIrradiation of recurrent Brain Metastases (RIBRAIM)”
      Sandra Amélia Moreira Mendes

  • 16h30 | Coffee-Break


  • 16h45 | STUDENTS’ PRESENTATIONS
    Tumor Biology

    Chairs: Carmen Jerónimo (IPO Porto/ICBAS-UP) & Rui Medeiros (IPO Porto/UFP/ICBAS-UP)
    • 16h45 | “Using Genome-Wide CRISPR Screens to Dissect the Molecular Mechanisms Underlying Therapy Resistance and Sensitivity in HER2-Positive Gastric Cancer”
      Ana Catarina da Rocha Nunes
    • 17h00 | “Dissecting the Independent Roles of PRUNE2 and PCA3 in the Function of the PRUNE2/PCA3/AR Triad and Prostate Cancer Progression”
      Madalena Corado Ribeiro
    • 17h15 | “Effect of phytochemicals on nutrient uptake by pancreatic cancer cell lines”
      Sara Patrícia Gonçalves Pinto
    • 17h30 | “Targeting EGFR to modulate primary cilia in prostate cell lines harbouring ETS rearrangements”
      Sofia de Oliveira Costa

  • 17h45 | Closing Remarks


Registration

Closed Registration




ACKNOWLEDGMENTS

ICBAS
IPO-Porto
Centro de Investigação
LPCC

CONTACTS

EMAIL:

epop@ipoporto.min-saude.pt

TELEFONE:

225084100